Caspase 9 Ab
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Caspase 9 Ab
All lanes use the Antibody at 1:1000 dilution for 1 hour at room temperature.
Caspase 9 Ab
All lanes use the Antibody at 1:1000 dilution for 1 hour at room temperature.
Caspase 9 Ab
Western blot analysis of pro Caspase 9 expression in Jurkat cell lysate.
Caspase 9 Ab
Immunohistochemical analysis of paraffin-embedded human colon, using pro Caspase 9 Antibody.
Caspase 9 Ab
Caspase 9 Ab
Caspase 9 Ab
Caspase 9 Ab
Caspase 9 Ab
Caspase 9 Ab
Caspase 9 Ab
Caspase 9 Ab

产品简介

产品简介

Catalog No.

CY5749

Source

Recombinant Rabbit mAb

UniProt ID

P55211

Reactivity

Human

Application

WB;IHC;FC

Calculated Mol Weight

46 kDa

Observed Mol Weight

46 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

FC 1:20-1:100

Alternative Names

APAF-3; APAF3; Apoptotic protease Mch-6; ICE-LAP6; Apoptotic protease-activating factor 3; CASP-9; CASP9; Caspase-9 subunit p10; ICE-like apoptotic protease 6; ICELAP6; MCH6;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human Caspase 9

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).

引用文献

引用文献

Nifuroxazide suppresses PD-L1 expression and enhances the efficacy of radiotherapy in hepatocellular carcinoma

期刊名称：

eLife

PMID：

38441416

影响因子：

6.4

应用范围：

WB,ICC/IF

检测物种：

Mouse,Human

发表时间：

2024-03-05

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CY5749

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

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