p63 Ab

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p63 Ab
p63 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
p63 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
p63 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
p63 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
p63 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
p63 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
p63 Ab
Western blot analysis of p63 expression in A431 cell lysate.
p63 Ab
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer, using the Antibody at 1:200 dilution.
p63 Ab
Immunohistochemical analysis of paraffin-embedded Human prostate cancer, using the Antibody at 1:200 dilution.
p63 Ab
Immunohistochemical analysis of paraffin-embedded Human small cell lung cancer , using the Antibody at 1:200 dilution.
p63 Ab
Immunohistochemical analysis of paraffin-embedded human breast, using p63 Antibody.

产品简介

产品简介

Catalog No.

CY5659

Source

Recombinant Rabbit mAb

UniProt ID

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;FC

Calculated Mol Weight

77 kDa

Observed Mol Weight

35-77 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

FC 1:20-1:100

Alternative Names

EEC3; KET; LMS; SHFM4; TA p63 alpha; TP63; p51; p73H; p73L; tumor protein p63;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human p63

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2.

引用文献

引用文献

期刊名称:

Oncogenesis

PMID:

30563971

影响因子:

4.722

应用范围:

WB

检测物种:

Human

发表时间:

2018-12-19

期刊名称:

Cell Death & Disease

PMID:

33833226

影响因子:

8.469

应用范围:

WB,IHC

检测物种:

Human

发表时间:

2021-04-08

期刊名称:

FEBS LETTERS

PMID:

36700826

影响因子:

3.5

应用范围:

WB,IHC

检测物种:

Mouse,Human

发表时间:

2023-01-26

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CY5659

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

现货

订购信息:

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