HES1 Ab
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HES1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
HES1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
HES1 Ab
HES1 Ab
Western blot analysis of Hes1 expression in SH-SY5Y cell lysate.
HES1 Ab

Immunohistochemical analysis of paraffin-embedded human liver, using Hes1 Antibody.

HES1 Ab

Immunofluorescent analysis using the Antibody at 1:50 dilution.

HES1 Ab
HES1 Ab
HES1 Ab
HES1 Ab
HES1 Ab
HES1 Ab

产品简介

产品简介

Catalog No.

CY5649

Source

Recombinant Rabbit mAb

UniProt ID

Q14469

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;FC

Calculated Mol Weight

30 kDa

Observed Mol Weight

30 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

FC 1:20-1:100

Alternative Names

HES1; BHLHb39; HHL; HL; Hairy and enhancer of split 1; Hairy homolog; HRY; Hairy homolog (Drosophila); Transcription factor HES-1; Hairy-like protein; HES-1;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human HES1

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

HES1 is one of seven members of the HES family of basic helix-loop-helix (bHLH) transcription factors which function primarily to repress transcription of bHLH-dependent genes. HES1 is understood to play an important conserved role in maintaining pluripotency of embryonic and adult stem/progenitor cells via the transcriptional repression of genes that promote differentiation.

引用文献

引用文献

Cystathionine-β-synthase (CBS)/H2S system promotes lymph node metastasis of esophageal squamous cell carcinoma (ESCC) by activating SIRT1

期刊名称：

CARCINOGENESIS

PMID：

34994384

影响因子：

4.741

应用范围：

WB,IHC

检测物种：

Mouse,Human

发表时间：

2022-01-05
DJ-1 Protein Inhibits Apoptosis in Cerebral Ischemia by Regulating the Notch1 and Nuclear Factor Erythroid2-Related Factor 2 Signaling Pathways

期刊名称：

NEUROSCIENCE

PMID：

36167256

影响因子：

3.708

应用范围：

WB

检测物种：

Rat

发表时间：

2022-09-24
AGRN promotes lung adenocarcinoma progression by activating Notch signaling pathway and acts as a therapeutic target

期刊名称：

PHARMACOLOGICAL RESEARCH

PMID：

37321467

影响因子：

9.3

应用范围：

WB,IHC

检测物种：

Mouse,Human,Rat

发表时间：

2023-06-13
N-Acetyltransferase 10 represses Uqcr11 and Uqcrb independently of ac4C modification to promote heart regeneration

期刊名称：

Nature Communications

PMID：

38459019

影响因子：

14.7

应用范围：

WB

检测物种：

Mouse

发表时间：

2024-03-08
Activation of Notch Signaling Pathway is involved in Extracellular Matrix Degradation in Human Induced Pluripotent Stem Cells Chondrocytes Induced by HT-2 Toxin

期刊名称：

FOOD AND CHEMICAL TOXICOLOGY

PMID：

38734200

影响因子：

3.9

应用范围：

IHC,WB

检测物种：

Human

发表时间：

2024-05-10
Benserazide, a cystathionine beta-synthase (CBS) inhibitor, potentially enhances the anticancer effects of paclitaxel via inhibiting the S-sulfhydration of SIRT1 and the HIF1-α/VEGF pathway

期刊名称：

Frontiers in Pharmacology

PMID：

38828455

影响因子：

4.4

应用范围：

WB,IP

检测物种：

Human

发表时间：

2024-05-17

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CY5649

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

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