ERK1/2 Ab - 上海埃必威生物技术有限公司

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ERK1/2 Ab

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All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

Western blot analysis of ERK1/2 Antibody expression in HepG2 whole cell lysates.

Polysaccharides from Nostoc commune Vaucher activate macrophages via NF-κB and AKT/JNK1/2 pathways to suppress colorectal cancer growth in vivo. -Food & Function

Critical role for non‑GAP function of Gαs in RGS1‑mediated promotion of melanoma progression through AKT and ERK phosphorylation. -Oncology Reports

CircDLST promotes the tumorigenesis and metastasis of gastric cancer by sponging miR-502-5p and activating the NRAS/MEK1/ERK1/2 signaling. -Molecular Cancer

Immunofluorescent analysis of Hela cells, using ERK1/2 Antibody.

产品简介

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产品简介

Catalog No.

CY5487

Source

Recombinant Rabbit mAb

UniProt ID

P27361/P28482

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF;IP;FC

Calculated Mol Weight

43,41 kDa

Observed Mol Weight

42, 44 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase 1, MAPK 1, p44-ERK1, ERT2, p44-MAPK, ERK-1,

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human ERK1

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Purification

Affinity-chromatography

Concentration

点击查询

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

引用文献

Critical role for non‑GAP function of Gαs in RGS1‑mediated promotion of melanoma progression through AKT and ERK phosphorylation

期刊名称：

ONCOLOGY REPORTS

PMID：

29620236

影响因子：

2.976

应用范围：

检测物种：

Human

发表时间：

2018-03-30

Succinate induces aberrant mitochondrial fission in cardiomyocytes through GPR91 signaling

期刊名称：

Cell Death & Disease

PMID：

29867110

影响因子：

5.638

应用范围：

检测物种：

Rat

发表时间：

2018-06-04

Euphorbia factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation in mice through the suppression of NF-κB activation

期刊名称：

BIOCHEMICAL PHARMACOLOGY

PMID：

30055150

影响因子：

4.235

应用范围：

检测物种：

Mouse

发表时间：

2018-07-26

CircDLST promotes the tumorigenesis and metastasis of gastric cancer by sponging miR-502-5p and activating the NRAS/MEK1/ERK1/2 signaling

期刊名称：

Molecular Cancer

PMID：

30953514

影响因子：

10.679

应用范围：

检测物种：

Human

发表时间：

2019-04-05

Polysaccharides from Nostoc commune Vaucher activate macrophages via NF-κB and AKT/JNK1/2 pathways to suppress colorectal cancer growth in vivo

期刊名称：

Food & Function

PMID：

31259992

影响因子：

3.241

应用范围：

检测物种：

Human,Mouse

发表时间：

2019-06-14

Phenols fragment of Veronica ciliata Fisch. ameliorate free radical-induced nonalcoholic fatty liver disease by mediating PI3K/Akt signaling pathway

期刊名称：

JOURNAL OF ETHNOPHARMACOLOGY

PMID：

31978521

影响因子：

3.69

应用范围：

检测物种：

Rat

发表时间：

2020-01-21

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CY5487

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

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