SOX9 Ab - 上海埃必威生物技术有限公司

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SOX9 Ab

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All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.

Western blot analysis of SOX9 expression in SW480 cell lysate.

Elevated H3K27me3 levels sensitize osteosarcoma to cisplatin. -Clinical Epigenetics

Immunohistochemical analysis of paraffin-embedded human colon, using SOX9 Antibody .

Immunofluorescent analysis of SW480 cells, using SOX9 Antibody .

产品简介

引用文献

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产品简介

Catalog No.

CY5400

Source

Recombinant Rabbit mAb

UniProt ID

P48436

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

56 kDa

Observed Mol Weight

70 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

Alternative Names

CMD1; Sox9; SRA1; SRXX2; SRXY10; SRY (sex determining region Y) box 9; Transcription factor SOX 9;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human SOX9

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Purification

Affinity-chromatography

Concentration

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Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Transcription factor that plays a key role in chondrocytes differentiation and skeletal development.Specifically binds the 5'-ACAAAG-3' DNA motif present in enhancers and super-enhancers and promotes expression of genes important for chondrogenesis, including cartilage matrix protein-coding genes COL2A1, COL4A2, COL9A1, COL11A2 and ACAN, SOX5 and SOX6.

引用文献

Degree of endplate chondrocyte degeneration in different tension regions during mechanical stimulation

期刊名称：

Molecular Medicine Reports

PMID：

29344659

影响因子：

1.922

应用范围：

检测物种：

Rat

发表时间：

2018-01-16

Conditioned media-integrated microneedles for hair regeneration through perifollicular angiogenesis

期刊名称：

JOURNAL OF CONTROLLED RELEASE

PMID：

35961471

影响因子：

11.467

应用范围：

ICC/IF

检测物种：

Mouse

发表时间：

2022-08-19

PROTAC Degraders of Androgen Receptor-Integrated Dissolving Microneedles for Androgenetic Alopecia and Recrudescence Treatment via Single Topical Administration

期刊名称：

Small Methods

PMID：

36538748

影响因子：

15.367

应用范围：

ICC/IF

检测物种：

Mouse

发表时间：

2022-12-20

Activated SOX9+ renal epithelial cells promote kidney repair through secreting factors

期刊名称：

CELL PROLIFERATION

PMID：

36601693

影响因子：

8.5

应用范围：

ICC/IF,WB

检测物种：

Mouse

发表时间：

2023-01-04

Co-immunization with DNA vaccines encoding yidR and IL-17 augments host immune response against Klebsiella pneumoniae infection in mouse model

期刊名称：

Virulence

PMID：

38656137

影响因子：

5.5

应用范围：

WB,ICC/IF,IHC

检测物种：

Escherichia coli,Mouse,Human

发表时间：

2024-04-24

Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis

期刊名称：

Theranostics

PMID：

39113800

影响因子：

12.4

应用范围：

WB,ICC/IF

检测物种：

Mouse

发表时间：

2024-07-08

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CY5400

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

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