PI3 kinase p85 alpha Ab
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PI3 kinase p85 alpha Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PI3 kinase p85 alpha Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PI3 kinase p85 alpha Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PI3 kinase p85 alpha Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PI3 kinase p85 alpha Ab
Western blot analysis of PI 3 Kinase p85 alpha expression in A431 cell lysate.
PI3 kinase p85 alpha Ab
PI3 kinase p85 alpha Ab
PI3 kinase p85 alpha Ab
PI3 kinase p85 alpha Ab
PI3 kinase p85 alpha Ab
PI3 kinase p85 alpha Ab
PI3 kinase p85 alpha Ab

产品简介

产品简介

Catalog No.

CY5355

Source

Recombinant Rabbit mAb

UniProt ID

P27986

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

84 kDa

Observed Mol Weight

85 kDa

Recommended Dilution

WB 1:1000-1:2000

Alternative Names

GRB1; P85A; PI3-kinase p85-alpha; PI3K; PI3K p85-alpha; ptdIns-3-kinase p85-alpha;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human PI3 kinase p85 alpha

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

引用文献

引用文献

LncRNA AK023391 promotes tumorigenesis and invasion of gastric cancer through activation of the PI3K/Akt signaling pathway

期刊名称：

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

PMID：

29282102

影响因子：

5.189

应用范围：

WB

检测物种：

Human

发表时间：

2017-12-28
Electro-acupuncture attenuates the mice premature ovarian failure via mediating PI3K/AKT/mTOR pathway

期刊名称：

LIFE SCIENCES

PMID：

30521869

影响因子：

3.234

应用范围：

WB

检测物种：

Mouse

发表时间：

2018-12-03
Effects of Compound 511 on BDNF-TrkB Signaling in the Mice Ventral Tegmental Area in Morphine-Induced Conditioned Place Preference

期刊名称：

CELLULAR AND MOLECULAR NEUROBIOLOGY

PMID：

32323150

影响因子：

3.606

应用范围：

WB

检测物种：

Mouse

发表时间：

2020-04-22
MicroRNA-26a inhibits wound healing through decreased keratinocytes migration by regulating ITGA5 through PI3K/AKT signaling pathway

期刊名称：

BIOSCIENCE REPORTS

PMID：

32955094

影响因子：

2.942

应用范围：

WB

检测物种：

Human

发表时间：

2020-09-29
Melatonin inhibits gallbladder cancer cell migration and invasion via ERK‑mediated induction of epithelial‑to‑mesenchymal transition

期刊名称：

Oncology Letters

PMID：

34188711

影响因子：

2.967

应用范围：

WB

检测物种：

Human

发表时间：

2021-06-15
A novel lncRNA ROPM-mediated lipid metabolism governs breast cancer stem cell properties

期刊名称：

Journal of Hematology & Oncology

PMID：

34715882

影响因子：

17.388

应用范围：

WB

检测物种：

Human

发表时间：

2021-10-29

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CY5355

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

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