DAP kinase 1 Ab

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DAP kinase 1 Ab
Western blot analysis of DAP Kinase 1 expression in HeLa cell lysate.
DAP kinase 1 Ab
Immunohistochemical analysis of paraffin-embedded human breast cancer, using DAP Kinase 1 Antibody.
DAP kinase 1 Ab
Immunofluorescent analysis of Hela cells, using DAP Kinase 1 Antibody .
DAP kinase 1 Ab
All lanes use the Antibody at 1:2k dilution for 1 hour at room temperature.
DAP kinase 1 Ab
All lanes use the Antibody at 1:2k dilution for 1 hour at room temperature.
DAP kinase 1 Ab
All lanes use the Antibody at 1:2k dilution for 1 hour at room temperature.
DAP kinase 1 Ab
DAP kinase 1 Ab
DAP kinase 1 Ab
DAP kinase 1 Ab
DAP kinase 1 Ab
DAP kinase 1 Ab

产品简介

产品简介

Catalog No.

CY5280

Source

Recombinant Rabbit mAb

UniProt ID

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

160 kDa

Observed Mol Weight

160 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

Alternative Names

DAK1; DAP K1; DAP kinase 1; DAPK 1; DAPK; DAPK1; DAPK1_HUMAN; Death Associated Protein Kinase 1; Death-associated protein kinase 1;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human DAP kinase 1

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. Phosphorylates TPM1, enhancing stress fiber formation in endothelial cells. Phosphorylates STX1A and significantly decreases its binding to STXBP1.

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CY5280

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

现货

订购信息:

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