p-SMAD3 (S423/S425) Ab
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p-SMAD3 (S423/S425) Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
p-SMAD3 (S423/S425) Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
p-SMAD3 (S423/S425) Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
p-SMAD3 (S423/S425) Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
p-SMAD3 (S423/S425) Ab
Western blot analysis of Phospho-Smad3 (S423/S425) expression in A549 cell lysate treated with TGF-ß1.
p-SMAD3 (S423/S425) Ab
Immunohistochemical analysis of paraffin-embedded human gastric adenocarcinoma, using Phospho-Smad3 (S423 + S425) Antibody.
p-SMAD3 (S423/S425) Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
p-SMAD3 (S423/S425) Ab
Immunofluorescent analysis of A549 cells treated with TGFβ , using Phospho-Smad3 (S423 + S425) Antibody.
p-SMAD3 (S423/S425) Ab
p-SMAD3 (S423/S425) Ab
p-SMAD3 (S423/S425) Ab
p-SMAD3 (S423/S425) Ab

产品简介

产品简介

Catalog No.

CY5140

Source

Recombinant Rabbit mAb

UniProt ID

P84022

Reactivity

Human;Mouse

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

48 kDa

Observed Mol Weight

55 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

Alternative Names

JV15-2, MAD-3, MADH3, Mad3, Mothers against DPP homolog 3, Mothers against decapentaplegic homolog 3, SMAD 3, Smad 3

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human SMAD3 around the phosphorylation site of S423/S425

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TGF-beta-mediated transcription.

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CY5140

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

订购信息：

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