Beclin 1 Ab
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Beclin 1 Ab
Western blot analysis of Beclin 1 expression in (1) HEK293 cell lysate; (2) NIH/3T3 cell lysate; (3) C6 cell lysate.
Beclin 1 Ab
Immunohistochemical analysis of paraffin-embedded human breast cancer, using Beclin 1 Antibody.
Beclin 1 Ab
Immunofluorescent analysis of Hela cells, using Beclin 1 Antibody.
Beclin 1 Ab
Beclin 1 Ab
Beclin 1 Ab
Beclin 1 Ab
Beclin 1 Ab
Beclin 1 Ab
Beclin 1 Ab
Beclin 1 Ab
Beclin 1 Ab

产品简介

产品简介

Catalog No.

CY5092

Source

Recombinant Rabbit mAb

UniProt ID

Q14457

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

52 kDa

Observed Mol Weight

55 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

Alternative Names

ATG6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; Beclin 1 autophagy related;Beclin-1;Beclin1; BECN1; Protein GT197; VPS30;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human Beclin 1

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.

引用文献

引用文献

Salidroside induces apoptosis and protective autophagy in human gastric cancer AGS cells through the PI3K/Akt/mTOR pathway

期刊名称：

BIOMEDICINE & PHARMACOTHERAPY

PMID：

31918283

影响因子：

3.743

应用范围：

WB

检测物种：

Human

发表时间：

2019-12-30
Phenols fragment of Veronica ciliata Fisch. ameliorate free radical-induced nonalcoholic fatty liver disease by mediating PI3K/Akt signaling pathway

期刊名称：

JOURNAL OF ETHNOPHARMACOLOGY

PMID：

31978521

影响因子：

3.69

应用范围：

WB

检测物种：

Rat

发表时间：

2020-01-21
Curcin C inhibit osteosarcoma cell line U2OS proliferation by ROS induced apoptosis, autophagy and cell cycle arrest through activating JNK signal pathway

期刊名称：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

PMID：

34896468

影响因子：

6.953

应用范围：

WB

检测物种：

Human

发表时间：

2021-12-09
Chaetoglobosin E inhibits tumor growth and promotes the anti-tumor efficacy of cytotoxic drugs in esophageal squamous cell carcinoma by targeting PLK1

期刊名称：

Annals of Translational Medicine

PMID：

36544631

影响因子：

3.616

应用范围：

WB

检测物种：

Human

发表时间：

2022-11-01
Exosomes derived from human umbilical cord mesenchymal stem cells pretreated by monosialoteterahexosyl ganglioside alleviate intracerebral hemorrhage by down-regulating autophagy

期刊名称：

EXPERIMENTAL CELL RESEARCH

PMID：

38311048

影响因子：

3.3

应用范围：

WB

检测物种：

Human,Rat

发表时间：

2024-02-03
Naringin safeguards vertebral endplate chondrocytes from apoptosis and NLRP3 inflammasome activation through SIRT3-mediated mitophagy

期刊名称：

INTERNATIONAL IMMUNOPHARMACOLOGY

PMID：

39121608

影响因子：

4.8

应用范围：

WB

检测物种：

Mouse

发表时间：

2024-08-08

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CY5092

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

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