MEK4 Ab
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MEK4 Ab
Western blot analysis of SEK1/MKK4 expression in NIH-3T3 whole cell lysates.The lane on the left is treated with the antigen-specific peptide.
MEK4 Ab
MEK4 Ab
MEK4 Ab
MEK4 Ab
MEK4 Ab
MEK4 Ab
MEK4 Ab
MEK4 Ab
MEK4 Ab
MEK4 Ab
MEK4 Ab

产品简介

产品简介

Catalog No.

CY3466

Source

Rabbit pAb

UniProt ID

P45985

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

44 kDa

Observed Mol Weight

44 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

C-JUN N-terminal kinase kinase 1, Dual specificity mitogen-activated protein kinase kinase 4, EC 2.7.12.2, JNK activating kinase 1, JNK kinase 1, JNKK, JNKK 1, JNKK1, MAP kinase kinase 4, MAP2K4, MAPK/ERK kinase 4, MAPKK 4, MKK4, MP2K4, PRKMK4, SAPK/ERK

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human MEK4

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

MKK4 dual specificity kinase of the STE7 family that phosphorylates and activates JNK1 and -2 as well as p38 but not ERK1 or -2. Mediates cellular responses to various cellular stresses and inflammatory cytokines. Phosphorylation by Akt inhibits MKK4 and suppresses stress-activated signal transduction.

引用文献

引用文献

Hepatoprotection of pine nut polysaccharide via NRF2/ARE/MKP1/JNK signaling pathways against carbon tetrachloride-induced liver injury in mice

期刊名称：

FOOD AND CHEMICAL TOXICOLOGY

PMID：

32540477

影响因子：

4.679

应用范围：

WB

检测物种：

Mouse

发表时间：

2020-06-12

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CY3466

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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