IL 6 receptor beta Ab
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IL 6 receptor beta Ab
Western blot analysis of extracts from Jurkat cells, using CD130/gp130 antibody.
IL 6 receptor beta Ab
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CD130/gp130 antibody.
IL 6 receptor beta Ab
Immunofluorescence analysis of NIH/3T3 cells, using CD130/gp130 antibody.
IL 6 receptor beta Ab
IL 6 receptor beta Ab
IL 6 receptor beta Ab
IL 6 receptor beta Ab
IL 6 receptor beta Ab
IL 6 receptor beta Ab
IL 6 receptor beta Ab
IL 6 receptor beta Ab
IL 6 receptor beta Ab

产品简介

产品简介

Catalog No.

CY3441

Source

Rabbit pAb

UniProt ID

P40189

Reactivity

Human;Mouse

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

104 kDa

Observed Mol Weight

160 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

ICC/IF 1:50-1:200

IHF 1:50-1:100

Alternative Names

CD130, CDw130, GP130, IL-6R-beta, IL6B, IL6RB, IL6ST, Interleukin 6 signal transducer, Interleukin-6 receptor beta chain precursor, Membrane glycoprotein 130, Oncostatin M receptor

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human IL 6 receptor beta

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Signal-transducing molecule.The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates the intracellular JAK-MAPK and JAK-STAT3 signaling pathways.That causes phosphorylation of IL6ST tyrosine residues which in turn activates STAT3.

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CY3441

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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