IRS 1 Ab
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IRS 1 Ab
Western blot analysis of IRS-1 expression in Jurkat cell lysates.The lane on the left is treated with the antigen-specific peptide.
IRS 1 Ab
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using IRS-1 Antibody. The picture on the right is treated with the synthesized peptide.
IRS 1 Ab
Immunofluorescence analysis of HeLa cells, using IRS-1 Antibody.
IRS 1 Ab
IRS 1 Ab
IRS 1 Ab
IRS 1 Ab
IRS 1 Ab
IRS 1 Ab
IRS 1 Ab
IRS 1 Ab
IRS 1 Ab

产品简介

产品简介

Catalog No.

CY3428

Source

Rabbit pAb

UniProt ID

P35568

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

132 kDa

Observed Mol Weight

132 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

ICC/IF 1:50-1:200

IHF 1:50-1:100

Alternative Names

IRS-1, IRS1, Insulin receptor substrate-1

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human IRS 1

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

IRS-1 is an adaptor protein that is one of the major substrates of the insulin receptor kinase. Contains multiple tyrosine phosphorylation motifs that serve as docking sites for SH2-domain-containing proteins including phosphatidylinositol 3-kinase p85 subunit and GRB-2.

引用文献

引用文献

Peroxisomal proliferator-activated receptor α-b deficiency induces the reprogramming of nutrient metabolism in zebrafish

期刊名称：

JOURNAL OF PHYSIOLOGY-LONDON

PMID：

32710562

影响因子：

4.547

应用范围：

WB

检测物种：

Zebrafish

发表时间：

2020-07-25
Inhibition of pyruvate dehydrogenase kinase improves carbohydrate utilization in Nile tilapia by regulating PDK2/4-PDHE1α axis and insulin sensitivity

期刊名称：

Animal Nutrition

PMID：

36016966

影响因子：

5.285

应用范围：

WB

检测物种：

Fish

发表时间：

2022-06-24

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CY3428

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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