DDR1 Ab

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DDR1 Ab
Western blot analysis of DDR1 expression in JK cells
DDR1 Ab
DDR1 Ab
DDR1 Ab
DDR1 Ab
DDR1 Ab
DDR1 Ab
DDR1 Ab
DDR1 Ab
DDR1 Ab
DDR1 Ab
DDR1 Ab

产品简介

产品简介

Catalog No.

CY2924

Source

Rabbit pAb

UniProt ID

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

101 kDa

Observed Mol Weight

110 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

NTRK4; Protein-tyrosine kinase 3A; Protein-tyrosine kinase RTK-6; PTK3; PTK3A; PTK3A protein tyrosine kinase 3A; RTK6; TRK E; TRKE; Tyrosine kinase DDR; Tyrosine-protein kinase CAK

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human DDR1

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Tyrosine kinase that functions as a cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing.

引用文献

引用文献

期刊名称:

Aging-US

PMID:

37709489

影响因子:

5.2

应用范围:

WB

检测物种:

Mouse

发表时间:

2023-09-14

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CY2924

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

次日发货

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