DR4 Ab
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DR4 Ab
Western blot analysis on K562 cell lysate using TR10A Antibody
DR4 Ab
DR4 Ab
DR4 Ab
DR4 Ab
DR4 Ab
DR4 Ab
DR4 Ab
DR4 Ab
DR4 Ab
DR4 Ab
DR4 Ab

产品简介

产品简介

Catalog No.

CY1411

Source

Rabbit pAb

UniProt ID

O00220

Reactivity

Human

Application

WB

Calculated Mol Weight

50 kDa

Observed Mol Weight

50 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

APO2; CD261; cytotoxic TRAIL receptor; Death receptor 4; DR4; MGC9365; TNF-related apoptosis inducing ligand receptor 1; TNF-related apoptosis-inducing ligand receptor 1; TNFRSF10A; TR10A; TRAIL receptor 1; TRAIL-R1; TRAILR-1; TRAILR1; Tumor necrosis fact

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human DR4

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:26457518).The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

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CY1411

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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