XPA Ab
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XPA Ab
Western blot analysis on COLO205 cell lysate using XPA Antibody
XPA Ab
XPA Ab
XPA Ab
XPA Ab
XPA Ab
XPA Ab
XPA Ab
XPA Ab
XPA Ab
XPA Ab
XPA Ab

产品简介

产品简介

Catalog No.

CY1400

Source

Rabbit pAb

UniProt ID

P23025

Reactivity

Human;Mouse

Application

WB;IHC

Calculated Mol Weight

31 kDa

Observed Mol Weight

40 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

DNA repair protein complementing XP-A cells; excision repair-controlling; Xeroderma pigmentosum group A-complementing protein; xeroderma pigmentosum, complementation group A; XP1; XPA; XPAC

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human XPA

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

XPA Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.

引用文献

引用文献

XPA serves as an autophagy and apoptosis inducer by suppressing hepatocellular carcinoma in a PI3K/Akt/mTOR dependent manner

期刊名称：

Journal of Gastrointestinal Oncology

PMID：

34532129

影响因子：

2.892

应用范围：

WB,IHC

检测物种：

Human

发表时间：

2021-08-01

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CY1400

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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