PTC Ab
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PTC Ab
Western blot analysis of extracts from mouse muscle cells, using Patched antibody.
PTC Ab
Western blot analysis of extracts from mouse 3T3 cells and HEPG2 cells, using Patched antibody.
PTC Ab
Immunohistochemical analysis of paraffin-embedded human brain tissue using Patched antibody.
PTC Ab
PTC Ab
PTC Ab
PTC Ab
PTC Ab
PTC Ab
PTC Ab
PTC Ab
PTC Ab

产品简介

产品简介

Catalog No.

CY1243

Source

Rabbit pAb

UniProt ID

Q13635

Reactivity

Human;Mouse

Application

WB;IHC

Calculated Mol Weight

161 kDa

Observed Mol Weight

160 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

BCNS; FLJ26746; FLJ42602; HPE7; NBCCS; patched homolog 1 (Drosophila); Protein patched homolog 1; PTC; PTC1; PTCH; PTCH protein +12b; PTCH protein +4'; PTCH protein -10; PTCH1; PTCH11

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human PTC

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.

引用文献

引用文献

Circular RNA Circ_0001322 inhibits gastric cancer progression by modulating the miR-1264/QKI axis and suppressing the Hedgehog pathway

期刊名称：

CELLULAR AND MOLECULAR BIOLOGY

PMID：

38814217

影响因子：

1.5

应用范围：

WB

检测物种：

Human

发表时间：

2024-05-27

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CY1243

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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