CDKN2A Ab
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CDKN2A Ab
Western blot analysis of extracts from HeLa cells, using p14 ARF antibody.
CDKN2A Ab
Immunohistochemical analysis of paraffin-embedded human placenta tissue using p14 ARF antibody.
CDKN2A Ab
Immunofluorescence analysis of HeLa cells, using p14 ARF antibody.
CDKN2A Ab
CDKN2A Ab
CDKN2A Ab
CDKN2A Ab
CDKN2A Ab
CDKN2A Ab
CDKN2A Ab
CDKN2A Ab
CDKN2A Ab

产品简介

产品简介

Catalog No.

CY1235

Source

Rabbit pAb

UniProt ID

Q8N726

Reactivity

Human

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

14 kDa

Observed Mol Weight

18 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

ICC/IF 1:50-1:200

IHF 1:50-1:100

Alternative Names

Tumor suppressor ARF; CDKN2A; Cyclin-dependent kinase inhibitor 2A; p14ARF; CDKN2; MLM;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human CDKN2A

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2-induced degradation of p53 and enhancing p53-dependent transactivation and apoptosis. Also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes.

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CY1235

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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