SMG5 Ab
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SMG5 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
SMG5 Ab
SMG5 Ab
SMG5 Ab
SMG5 Ab
SMG5 Ab
SMG5 Ab
SMG5 Ab
SMG5 Ab
SMG5 Ab
SMG5 Ab
SMG5 Ab

产品简介

产品简介

Catalog No.

BY2617

Source

Rabbit pAb

UniProt ID

Q9UPR3

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IP;FC

Calculated Mol Weight

114 kDa

Observed Mol Weight

140 kDa

Recommended Dilution

WB 1:1000-1:5000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

Nonsense-mediated mRNA decay factor SMG5;EST1B;KIAA1089

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human SMG5

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity.

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BY2617

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

订购信息：

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