KLHL3 Ab
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KLHL3 Ab
Western blot analysis of extracts from RAW264.7 cells and 3T3 cells, using KLHL3 antibody.
KLHL3 Ab
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using KLHL3 antibody.
KLHL3 Ab
Immunofluorescence analysis of A549 cells, using KLHL3 antibody.
KLHL3 Ab
KLHL3 Ab
KLHL3 Ab
KLHL3 Ab
KLHL3 Ab
KLHL3 Ab
KLHL3 Ab
KLHL3 Ab
KLHL3 Ab

产品简介

产品简介

Catalog No.

AY4734

Source

Rabbit pAb

UniProt ID

Q9UH77

Reactivity

Human

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

65 kDa

Observed Mol Weight

65 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

ICC/IF 1:50-1:200

IHF 1:50-1:100

Alternative Names

Kelch-like protein 3; KIAA1129

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human KLHL3

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron.The BCR(KLHL3) complex acts by mediating ubiquitination and degradation of WNK1 and WNK4, two activators of Na-Cl cotransporter SLC12A3/NCC in distal convoluted tubule cells of kidney, thereby regulating NaCl reabsorption.

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AY4734

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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