UBR1 Ab
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UBR1 Ab
Western blot analysis of extracts from Jurkat cells and HepG2 cells, using UBR1 antibody.
UBR1 Ab
UBR1 Ab
UBR1 Ab
UBR1 Ab
UBR1 Ab
UBR1 Ab
UBR1 Ab
UBR1 Ab
UBR1 Ab
UBR1 Ab
UBR1 Ab

产品简介

产品简介

Catalog No.

AY4537

Source

Rabbit pAb

UniProt ID

Q8IWV7

Reactivity

Human;Mouse

Application

WB

Calculated Mol Weight

200 kDa

Observed Mol Weight

36 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

EC 6.3.2.-; Ubiquitin ligase E3 alpha-I Storage/Stability: Store at -20℃/1 year

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human UBR1

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May be involved in pancreatic homeostasis. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.

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AY4537

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

订购信息：

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