UBASH3A Ab

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UBASH3A Ab
Western blot analysis of extracts from LOVO cells, HuvEc cells and K562 cells, using UBASH3A antibody.
UBASH3A Ab
UBASH3A Ab
UBASH3A Ab
UBASH3A Ab
UBASH3A Ab
UBASH3A Ab
UBASH3A Ab
UBASH3A Ab
UBASH3A Ab
UBASH3A Ab
UBASH3A Ab

产品简介

产品简介

Catalog No.

AY4525

Source

Rabbit pAb

UniProt ID

Reactivity

Human

Application

WB

Calculated Mol Weight

74 kDa

Observed Mol Weight

74 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

Suppressor of T-cell receptor signaling 2; STS-2; Cbl-interacting protein 4; CLIP4; T-cell ubiquitin ligand; TULA

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human UBASH3A

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligible protein tyrosine phosphatase activity at neutral pH. May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.

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AY4525

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

次日发货

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