TLK1 Ab
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TLK1 Ab
Western blot analysis of extracts from rat brain cells and NIH/3T3 cells, using TLK1 antibody.
TLK1 Ab
TLK1 Ab
TLK1 Ab
TLK1 Ab
TLK1 Ab
TLK1 Ab
TLK1 Ab
TLK1 Ab
TLK1 Ab
TLK1 Ab
TLK1 Ab

产品简介

产品简介

Catalog No.

AY4409

Source

Rabbit pAb

UniProt ID

Q9UKI8

Reactivity

Human

Application

WB

Calculated Mol Weight

87 kDa

Observed Mol Weight

87 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

kinase TLK1; PKU-beta; tousled-like kinase 1

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human TLK1

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by facilitating the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10'.

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AY4409

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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