STAT1 Ab

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STAT1 Ab
Western blot analysis of extracts from MCF7 cells using,using STAT1 antibody.
STAT1 Ab
STAT1 Ab
STAT1 Ab
STAT1 Ab
STAT1 Ab
STAT1 Ab
STAT1 Ab
STAT1 Ab
STAT1 Ab
STAT1 Ab
STAT1 Ab

产品简介

产品简介

Catalog No.

AY4260

Source

Rabbit pAb

UniProt ID

Reactivity

Human;Mouse;Rat

Application

WB;IHC

Calculated Mol Weight

87 kDa

Observed Mol Weight

83 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

STAT1;DKFZp686B04100;ISGF-3;STAT91 ;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human STAT1

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus.

引用文献

引用文献

期刊名称:

Journal of Neuroinflammation

PMID:

34183017

影响因子:

8.322

应用范围:

WB

检测物种:

Mouse

发表时间:

2021-06-28

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AY4260

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

次日发货

订购信息:

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