RRM2B Ab
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RRM2B Ab
RRM2B Ab
RRM2B Ab
RRM2B Ab
RRM2B Ab
RRM2B Ab
RRM2B Ab
RRM2B Ab
RRM2B Ab
RRM2B Ab
RRM2B Ab
RRM2B Ab

产品简介

产品简介

Catalog No.

AY4010

Source

Rabbit pAb

UniProt ID

Q7LG56

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

41 kDa

Observed Mol Weight

41 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

DKFZp686M05248; MGC102856; MGC42116; p53-inducible ribonucleotide reductase small subunit 2 homolog; p53-inducible ribonucleotide reductase small subunit 2-like protein; P53R2; Ribonucleoside-diphosphate reductase subunit M2 B; ribonucleotide reductase M

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human RRM2B

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.

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AY4010

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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