RhoB Ab
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RhoB Ab
Western blot analysis of extracts from HepG2 cells and HeLa cells, using RHOB antibody.
RhoB Ab
RhoB Ab
RhoB Ab
RhoB Ab
RhoB Ab
RhoB Ab
RhoB Ab
RhoB Ab
RhoB Ab
RhoB Ab
RhoB Ab

产品简介

产品简介

Catalog No.

AY3924

Source

Rabbit pAb

UniProt ID

P62745

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

22 kDa

Observed Mol Weight

22 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

H6; Rho-related GTP-binding protein RhoB; RHOB; ARH6; ARHB

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human RhoB

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.

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AY3924

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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