PTPN22 Ab

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PTPN22 Ab
PTPN22 Ab
PTPN22 Ab
PTPN22 Ab
PTPN22 Ab
PTPN22 Ab
PTPN22 Ab
PTPN22 Ab
PTPN22 Ab
PTPN22 Ab
PTPN22 Ab
PTPN22 Ab

产品简介

产品简介

Catalog No.

AY3795

Source

Rabbit pAb

UniProt ID

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

92 kDa

Observed Mol Weight

92 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP; Lymphoid phosphatase; lymphoid-specific protein tyrosine phosphatase; LyP; LYP1; LYP2; PEP; PEST-domain phosphatase; protein tyrosine phosphatase, non-receptor type 22 (lymphoid); protein tyrosine p

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human PTPN22

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Acts as a negative regulator of T-cell receptor (TCR) signaling by direct dephosphorylation of the Src family kinases LCK and FYN, ITAMs of the TCRz/CD3 complex, as well as ZAP70, VAV, VCP and other key signaling molecules.Associates with and probably dephosphorylates CBL. Dephosphorylates LCK at its activating 'Tyr-394' residue.

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AY3795

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

次日发货

订购信息:

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