PDK2 Ab
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PDK2 Ab
Western blot analysis of extracts from HepG2 cells, using PDK2 antibody.
PDK2 Ab
PDK2 Ab
PDK2 Ab
PDK2 Ab
PDK2 Ab
PDK2 Ab
PDK2 Ab
PDK2 Ab
PDK2 Ab
PDK2 Ab
PDK2 Ab

产品简介

产品简介

Catalog No.

AY3550

Source

Rabbit pAb

UniProt ID

Q15119

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

46 kDa

Observed Mol Weight

46 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

EC 2.7.11.2; kinase Pyruvate dehydrogenase kinase 2; PDK2; Pyruvate dehydrogenase [lipoamide] kinase isozyme 2, mitochondrial precursor

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human PDK2

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Kinase that plays a key role in the regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Inhibition of pyruvate dehydrogenase decreases glucose utilization and increases fat metabolism. Mediates cellular responses to insulin.

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AY3550

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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