MLH1 Ab
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MLH1 Ab
Western blot analysis of extracts from K562 cells, using MLH1 antibody.
MLH1 Ab
MLH1 Ab
MLH1 Ab
MLH1 Ab
MLH1 Ab
MLH1 Ab
MLH1 Ab
MLH1 Ab
MLH1 Ab
MLH1 Ab
MLH1 Ab

产品简介

产品简介

Catalog No.

AY2999

Source

Rabbit pAb

UniProt ID

P40692

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

85 kDa

Observed Mol Weight

85 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

DNA mismatch repair protein Mlh1, MutL protein homolog 1, MLH1, COCA2

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human MLH1

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH3) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2.

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AY2999

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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