GRK6 Ab
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GRK6 Ab
Western blot analysis of extracts from Jurkat cells, COLO205 cells and HUVEC cells, using GRK6 antibody.
GRK6 Ab
Immunofluorescence analysis of HeLa cells, using GRK6 antibody.
GRK6 Ab
GRK6 Ab
GRK6 Ab
GRK6 Ab
GRK6 Ab
GRK6 Ab
GRK6 Ab
GRK6 Ab
GRK6 Ab
GRK6 Ab

产品简介

产品简介

Catalog No.

AY2443

Source

Rabbit pAb

UniProt ID

P43250

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF

Calculated Mol Weight

66 kDa

Observed Mol Weight

65 kDa

Recommended Dilution

WB 1:500-1:1000

ICC/IF 1:50-1:200

Alternative Names

EC 2.7.11.16, G-protein-coupled receptor kinase 6, GPRK6, kinase GRK6

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human GRK6

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis.Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).

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AY2443

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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