CRFR 1 Ab
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CRFR 1 Ab
CRFR 1 Ab
CRFR 1 Ab
CRFR 1 Ab
CRFR 1 Ab
CRFR 1 Ab
CRFR 1 Ab
CRFR 1 Ab
CRFR 1 Ab
CRFR 1 Ab
CRFR 1 Ab
CRFR 1 Ab

产品简介

产品简介

Catalog No.

AY1786

Source

Rabbit pAb

UniProt ID

P34998

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF

Calculated Mol Weight

51 kDa

Observed Mol Weight

50 kDa

Recommended Dilution

WB 1:500-1:1000

ICC/IF 1:50-1:200

Alternative Names

Corticotropin releasing factor receptor 1 precursor; Corticotropin-releasing hormone receptor 1; CRF-R; CRF1; CRFR; CRFR1; CRH-R 1; CRHR; CRHR1

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human CRFR 1

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.

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AY1786

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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