CMTM6 Ab
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CMTM6 Ab
Western blot analysis of extracts from RAW264.7 cells, using CKLF6 antibody.
CMTM6 Ab
CMTM6 Ab
CMTM6 Ab
CMTM6 Ab
CMTM6 Ab
CMTM6 Ab
CMTM6 Ab
CMTM6 Ab
CMTM6 Ab
CMTM6 Ab
CMTM6 Ab

产品简介

产品简介

Catalog No.

AY1696

Source

Rabbit pAb

UniProt ID

Q9NX76

Reactivity

Human

Application

WB

Calculated Mol Weight

20 kDa

Observed Mol Weight

24 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

CKLF-like MARVEL transmembrane domain-containing protein 6; Chemokine-like factor superfamily member 6; CMTM6; CKLFSF6

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human CMTM6

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its STUB1-mediated ubiquitination.

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AY1696

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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