CHFR Ab
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CHFR Ab
CHFR Ab
CHFR Ab
CHFR Ab
CHFR Ab
CHFR Ab
CHFR Ab
CHFR Ab
CHFR Ab
CHFR Ab
CHFR Ab
CHFR Ab

产品简介

产品简介

Catalog No.

AY1663

Source

Rabbit pAb

UniProt ID

Q96EP1

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

73 kDa

Observed Mol Weight

80 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

checkpoint with forkhead and ring finger domains; Checkpoint with forkhead and RING finger domains protein; CHFR; E3 ubiquitin-protein ligase CHFR; FLJ10796; FLJ33629; RING finger protein 196; RNF116; RNF196

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human CHFR

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons. Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus. Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the 'Lys-48'-linked ubiquitination of target proteins, leading to their degradation by the proteasome.

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AY1663

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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