CELF 1 Ab
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CELF 1 Ab
Western blot analysis of extracts from HeLa cells and HepG2 cells, using CELF-1 antibody.
CELF 1 Ab
CELF 1 Ab
CELF 1 Ab
CELF 1 Ab
CELF 1 Ab
CELF 1 Ab
CELF 1 Ab
CELF 1 Ab
CELF 1 Ab
CELF 1 Ab
CELF 1 Ab

产品简介

产品简介

Catalog No.

AY1636

Source

Rabbit pAb

UniProt ID

Q92879

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

52 kDa

Observed Mol Weight

52 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

CELF-1, Bruno-like protein 2, RNA-binding protein BRUNOL-2, CUG triplet repeat RNA-binding protein 1, CUG-BP1, Deadenylation factor CUG-BP, 50 kDa nuclear polyadenylated RNA-binding protein, Embryo deadenylation element-binding protein homolog, EDEN-BP ho

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human CELF 1

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts both as an activator and as a repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon but exclusion of the non-muscle (NM) exon in actinin pre-mRNAs. Activates SM exon 5 inclusion by antagonizing the repressive effect of PTB.

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AY1636

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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