CDK5 activator 1 Ab
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CDK5 activator 1 Ab
Western blot analysis of extracts from rat brain cells, using CDK5R1 antibody.
CDK5 activator 1 Ab
CDK5 activator 1 Ab
CDK5 activator 1 Ab
CDK5 activator 1 Ab
CDK5 activator 1 Ab
CDK5 activator 1 Ab
CDK5 activator 1 Ab
CDK5 activator 1 Ab
CDK5 activator 1 Ab
CDK5 activator 1 Ab
CDK5 activator 1 Ab

产品简介

产品简介

Catalog No.

AY1615

Source

Rabbit pAb

UniProt ID

Q15078

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF

Calculated Mol Weight

34 kDa

Observed Mol Weight

38 kDa

Recommended Dilution

WB 1:500-1:1000

ICC/IF 1:50-1:200

Alternative Names

CD5R, CD5R1, CDK5 activator 1, CDK5R, Cyclin-dependent kinase 5 activator 1 precursor, Cyclin-dependent kinase 5 regulatory subunit 1, NCK5A, P23, P25, P35, TPKII regulatory subunit, Tau protein kinase II 23 kDa subunit

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human CDK5 activator 1

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-BMAL1 heterodimer in association with altered stability and subcellular distribution.

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AY1615

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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