ASCL2 Ab
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ASCL2 Ab
Western blot analysis of extracts from K562 cells, using ASCL2 antibody.
ASCL2 Ab
ASCL2 Ab
ASCL2 Ab
ASCL2 Ab
ASCL2 Ab
ASCL2 Ab
ASCL2 Ab
ASCL2 Ab
ASCL2 Ab
ASCL2 Ab
ASCL2 Ab

产品简介

产品简介

Catalog No.

AY0948

Source

Rabbit pAb

UniProt ID

Q99929

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

20 kDa

Observed Mol Weight

25 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

achaete-scute complex homolog 2(Drosophila); achaete-scute complex-like 2;Achaete-scute homolog 2; ASCL2; ASH-2; ASH2;BHLHA45; Class A basic helix-loop-helix protein 45; HASH2; mammalian achaete/scute homologue 2; Mash2;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human ASCL2

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Transcription factor. Binds to E-box motifs 5'-CANNTG-3' in the regulatory elements of target genes, probably as a heterodimer with another basic helix-loop-helix (bHLH) protein such as the transcription factor TCF3. May bind both open and closed chromatin, acting as a pioneer transcription factor to allow other factors to bind and activate lineage-specific genes.

引用文献

引用文献

ASCL2 Affects the Efficacy of Immunotherapy in Colon Adenocarcinoma Based on Single-Cell RNA Sequencing Analysis

期刊名称：

Frontiers in Immunology

PMID：

35774798

影响因子：

8.786

应用范围：

WB

检测物种：

Human

发表时间：

2022-06-03

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AY0948

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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