p-COP1 (S387) Ab
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p-COP1 (S387) Ab
Western blot analysis of extracts from K562 cells, treated with UV (15mins), using RFWD2 (Phospho-Ser387) antibody.
p-COP1 (S387) Ab
p-COP1 (S387) Ab
p-COP1 (S387) Ab
p-COP1 (S387) Ab
p-COP1 (S387) Ab
p-COP1 (S387) Ab
p-COP1 (S387) Ab
p-COP1 (S387) Ab
p-COP1 (S387) Ab
p-COP1 (S387) Ab
p-COP1 (S387) Ab

产品简介

产品简介

Catalog No.

AY0873

Source

Rabbit pAb

UniProt ID

Q8NHY2

Reactivity

Human;Mouse

Application

WB

Calculated Mol Weight

80 kDa

Observed Mol Weight

101 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

Constitutive photomorphogenesis protein 1 homolog; COP1; EC 6.3.2.-; hCOP1; RING finger and WD repeat domain protein 2; Ubiquitin- protein ligase COP1

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human COP1 around the phosphorylation site of S387

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Involved in JUN ubiquitination and degradation. Directly involved in p53 (TP53) ubiquitination and degradation, thereby abolishing p53-dependent transcription and apoptosis.

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AY0873

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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