p-Fadd (S191) Ab

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p-Fadd (S191) Ab
Western blot analysis of extracts from Jurkat cells, treated with PMA (125ng/ml, 30mins), using FADD (Phospho-Ser191) antibody.
p-Fadd (S191) Ab
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using FADD (Phospho-Ser191) antibody.
p-Fadd (S191) Ab
p-Fadd (S191) Ab
p-Fadd (S191) Ab
p-Fadd (S191) Ab
p-Fadd (S191) Ab
p-Fadd (S191) Ab
p-Fadd (S191) Ab
p-Fadd (S191) Ab
p-Fadd (S191) Ab
p-Fadd (S191) Ab

产品简介

产品简介

Catalog No.

AY0779

Source

Rabbit pAb

UniProt ID

Reactivity

Mouse

Application

WB;IHC

Calculated Mol Weight

23 kDa

Observed Mol Weight

23 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

FAS-associating death domain-containing protein; Mediator of receptor induced toxicity; MORT1

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from mouse Fadd around the phosphorylation site of S191

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Apoptotic adapter molecule that recruits caspases CASP8 or CASP10 to the activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

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AY0779

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

次日发货

订购信息:

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