4E BP1 Ab

一键复制产品信息

4E BP1 Ab
Western blot analysis of extracts from COS7 cells, treated with EGF (200ng/ml, 30mins), using 4E-BP1 antibody.
4E BP1 Ab
Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using 4E-BP1 antibody.
4E BP1 Ab
4E BP1 Ab
4E BP1 Ab
4E BP1 Ab
4E BP1 Ab
4E BP1 Ab
4E BP1 Ab
4E BP1 Ab
4E BP1 Ab
4E BP1 Ab

产品简介

产品简介

Catalog No.

AY0776

Source

Rabbit pAb

UniProt ID

Reactivity

Mouse;Rat

Application

WB;IHC

Calculated Mol Weight

12 kDa

Observed Mol Weight

12 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

4EBP1, EIF4EBP1, Eukaryotic translation initiation factor 4E binding protein 1, Insulin-stimulated EIF-4E binding protein PHAS-I, P/OKCL.6, PHAS-1, PHAS-I

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from mouse 4E BP1

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation (By similarity).

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AY0776

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

次日发货

订购信息:

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