SMAD2 Ab
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SMAD2 Ab
Western blot analysis of extracts from RAW264.7 cells and 293 cells, using Smad2 antibody.
SMAD2 Ab
SMAD2 Ab
SMAD2 Ab
SMAD2 Ab
SMAD2 Ab
SMAD2 Ab
SMAD2 Ab
SMAD2 Ab
SMAD2 Ab
SMAD2 Ab
SMAD2 Ab

产品简介

产品简介

Catalog No.

AY0739

Source

Rabbit pAb

UniProt ID

Q15796

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

52 kDa

Observed Mol Weight

58 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

ICC/IF 1:50-1:200

IHF 1:50-1:100

Alternative Names

JV18-1, MADH2, MADR2, Mad-related protein 2, Mothers against DPP homolog 2, Mothers against decapentaplegic homolog 2, Smad 2

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human SMAD2

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. Promotes TGFB1-mediated transcription of odontoblastic differentiation genes in dental papilla cells (By similarity).

引用文献

引用文献

Sinomenine Relieves Airway Remodeling By Inhibiting Epithelial-Mesenchymal Transition Through Downregulating TGF-β1 and Smad3 Expression In Vitro and In Vivo

期刊名称：

Frontiers in Immunology

PMID：

34804018

影响因子：

7.561

应用范围：

IHC,WB

检测物种：

Mouse,Human

发表时间：

2021-11-05

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AY0739

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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