p-MDC1 (S513) Ab
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p-MDC1 (S513) Ab
Immunohistochemistry analysis of paraffin-embedded human brain tissue using MDC1 (Phospho-Ser513) antibody.
p-MDC1 (S513) Ab
p-MDC1 (S513) Ab
p-MDC1 (S513) Ab
p-MDC1 (S513) Ab
p-MDC1 (S513) Ab
p-MDC1 (S513) Ab
p-MDC1 (S513) Ab
p-MDC1 (S513) Ab
p-MDC1 (S513) Ab
p-MDC1 (S513) Ab
p-MDC1 (S513) Ab

产品简介

产品简介

Catalog No.

AY0711

Source

Rabbit pAb

UniProt ID

Q14676

Reactivity

Human

Application

IHC

Calculated Mol Weight

227 kDa

Observed Mol Weight

227 kDa

Recommended Dilution

IHC 1:50-1:100

Alternative Names

DKFZp781A0122; IER3; KIAA0170; mediator of DNA damage checkpoint 1; MGC166888; NFBD1

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human MDC1 around the phosphorylation site of S513

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Histone reader protein required for checkpoint-mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle.Specifically recognizes and binds histone H2AX phosphorylated at 'Ser-139', a marker of DNA damage, serving as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage sites.

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AY0711

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

订购信息：

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