p-MDC1 (S513) Ab

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p-MDC1 (S513) Ab
Immunohistochemistry analysis of paraffin-embedded human brain tissue using MDC1 (Phospho-Ser513) antibody.
p-MDC1 (S513) Ab
p-MDC1 (S513) Ab
p-MDC1 (S513) Ab
p-MDC1 (S513) Ab
p-MDC1 (S513) Ab
p-MDC1 (S513) Ab
p-MDC1 (S513) Ab
p-MDC1 (S513) Ab
p-MDC1 (S513) Ab
p-MDC1 (S513) Ab
p-MDC1 (S513) Ab

产品简介

产品简介

Catalog No.

AY0711

Source

Rabbit pAb

UniProt ID

Reactivity

Human

Application

IHC

Calculated Mol Weight

227 kDa

Observed Mol Weight

227 kDa

Recommended Dilution

IHC 1:50-1:100

Alternative Names

DKFZp781A0122; IER3; KIAA0170; mediator of DNA damage checkpoint 1; MGC166888; NFBD1

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human MDC1 around the phosphorylation site of S513

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Histone reader protein required for checkpoint-mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle.Specifically recognizes and binds histone H2AX phosphorylated at 'Ser-139', a marker of DNA damage, serving as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage sites.

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AY0711

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

次日发货

订购信息:

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