p-DDR1 (Y513) Ab

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p-DDR1 (Y513) Ab
Western blot analysis of extracts from HepG2 cells, treated with Na3VO4 (0.3mM, 40mins), using DDR1 (Phospho-Tyr513) antibody.
p-DDR1 (Y513) Ab
Immunohistochemistry analysis of paraffin-embedded human brain tissue using DDR1 (Phospho-Tyr513) antibody.
p-DDR1 (Y513) Ab
p-DDR1 (Y513) Ab
p-DDR1 (Y513) Ab
p-DDR1 (Y513) Ab
p-DDR1 (Y513) Ab
p-DDR1 (Y513) Ab
p-DDR1 (Y513) Ab
p-DDR1 (Y513) Ab
p-DDR1 (Y513) Ab
p-DDR1 (Y513) Ab

产品简介

产品简介

Catalog No.

AY0647

Source

Rabbit pAb

UniProt ID

Reactivity

Human;Mouse;Rat

Application

WB;IHC

Calculated Mol Weight

101 kDa

Observed Mol Weight

107 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

CAK; CD167a antigen; Cell adhesion kinase; Discoidin receptor tyrosine kinase; EC 2.7.1.112; EC 2.7.10.1; EDDR1; Epithelial discoidin domain receptor 1 precursor; HGK2; Protein-tyrosine kinase RTK 6; RTK6; TRK E; TRKE; Tyrosine kinase DDR; Tyrosine- protein kinase CAK

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human DDR1 around the phosphorylation site of Y513

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Tyrosine kinase that functions as a cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing.

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AY0647

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

次日发货

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