p-BAX (S184) Ab

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p-BAX (S184) Ab
Western blot analysis of extracts from K562 cells, using Bax (Phospho-Ser184) antibody.
p-BAX (S184) Ab
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Bax (Phospho-Ser184) antibody.
p-BAX (S184) Ab
p-BAX (S184) Ab
p-BAX (S184) Ab
p-BAX (S184) Ab
p-BAX (S184) Ab
p-BAX (S184) Ab
p-BAX (S184) Ab
p-BAX (S184) Ab
p-BAX (S184) Ab
p-BAX (S184) Ab

产品简介

产品简介

Catalog No.

AY0638

Source

Rabbit pAb

UniProt ID

Reactivity

Human;Mouse;Rat

Application

WB;IHC

Calculated Mol Weight

21 kDa

Observed Mol Weight

21 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

Apoptosis regulator BAX, membrane isoform alpha; BAXA; Bcl2-associated X protein

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human BAX around the phosphorylation site of S184

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.

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AY0638

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

次日发货

订购信息:

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