Cleaved-ADAM 17 (R215) Ab
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Cleaved-ADAM 17 (R215) Ab
Western blot analysis of extracts from rat liver cells, using ADAM 17 (Cleaved-Arg215) antibody.
Cleaved-ADAM 17 (R215) Ab
Cleaved-ADAM 17 (R215) Ab
Cleaved-ADAM 17 (R215) Ab
Cleaved-ADAM 17 (R215) Ab
Cleaved-ADAM 17 (R215) Ab
Cleaved-ADAM 17 (R215) Ab
Cleaved-ADAM 17 (R215) Ab
Cleaved-ADAM 17 (R215) Ab
Cleaved-ADAM 17 (R215) Ab
Cleaved-ADAM 17 (R215) Ab
Cleaved-ADAM 17 (R215) Ab

产品简介

产品简介

Catalog No.

AY0591

Source

Rabbit pAb

UniProt ID

P78536

Reactivity

Human;Rat

Application

WB

Calculated Mol Weight

68,93 kDa

Observed Mol Weight

68, 93 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

a disintegrin and metalloproteinase domain 17; ADA17; ADAM 17; CD156b antigen; CSVP; EC 3.4.24.86; snake venom-like protease; TACE; TNF-alpha convertase; TNF-alpha-converting enzyme

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Other

Immunogen

A synthesized peptide derived from human ADAM 17

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

TACE is responsible for the shedding of EGFR ligands such as amphiregulin and TNF-α. Some tumors have hyperactivated EGFR due to upregulated TNF-α production and upregulated TACE, making TACE a potential target for drug development. TACE activates Notch in a ligand-independent manner and has been shown to play a role in the development of the Drosophila nervous system.

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AY0591

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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