p-TERF1 (S219) Ab
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p-TERF1 (S219) Ab
Lane 1: The extracts from 293 cells treated with paclitaxel (1uM, 24hours) using Telomeric Repeat Binding Factor 1 (Phospho-Ser219) antibody Lane 2: The extracts from 293 cells treated with paclitaxel (1uM, 24hours) plus phosphopeptide using Telomeric Repeat Binding Factor 1 (Phospho-Ser219) antibody Lane 3: The extracts from293 cells treated with paclitaxel (1uM, 24hours) using Telomeric Repeat Binding Factor 1 antibody.
p-TERF1 (S219) Ab
p-TERF1 (S219) Ab
p-TERF1 (S219) Ab
p-TERF1 (S219) Ab
p-TERF1 (S219) Ab
p-TERF1 (S219) Ab
p-TERF1 (S219) Ab
p-TERF1 (S219) Ab
p-TERF1 (S219) Ab
p-TERF1 (S219) Ab
p-TERF1 (S219) Ab

产品简介

产品简介

Catalog No.

AY0539

Source

Rabbit pAb

UniProt ID

P54274

Reactivity

Human;Mouse

Application

WB

Calculated Mol Weight

50 kDa

Observed Mol Weight

56 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

NIMA-interacting protein 2; PIN2; Telomeric protein Pin2/TRF1; Telomeric repeat binding factor 1; TERF1; TRF; TTAGGG repeat binding factor 1

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human TERF1 around the phosphorylation site of S219

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Plays an influential role in cellular immortalization and cellular senescence. TRF1 negatively regulates telomere elongation, while TRF2 protects the chromosome ends by inhibiting end-to-end fusions. Down-regulation of TRF expression in tumor cells may contribute to cell immortalization and malignant progression.

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AY0539

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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