p-IRAK1 (S376) Ab

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p-IRAK1 (S376) Ab
Immunohistochemistry analysis of paraffin-embedded human brain tissue using IRAK1 (Phospho-Ser376) antibody.
p-IRAK1 (S376) Ab
p-IRAK1 (S376) Ab
p-IRAK1 (S376) Ab
p-IRAK1 (S376) Ab
p-IRAK1 (S376) Ab
p-IRAK1 (S376) Ab
p-IRAK1 (S376) Ab
p-IRAK1 (S376) Ab
p-IRAK1 (S376) Ab
p-IRAK1 (S376) Ab
p-IRAK1 (S376) Ab

产品简介

产品简介

Catalog No.

AY0520

Source

Rabbit pAb

UniProt ID

Reactivity

Human

Application

IHC

Calculated Mol Weight

77 kDa

Observed Mol Weight

77 kDa

Recommended Dilution

IHC 1:50-1:100

Alternative Names

IL1RAK, IRAK, IRAK-1, Interleukin-1 receptor-associated kinase 1, Pelle-like protein kinase, kinase IRAK1, Mplk

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human IRAK1 around the phosphorylation site of S376

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation. Association with MYD88 leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation.

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AY0520

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

次日发货

订购信息:

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