p-IRAK1 (T209) Ab
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p-IRAK1 (T209) Ab
Western blot analysis of extracts from HeLa cells, using IRAK1 (Phospho-Thr209) antibody.
p-IRAK1 (T209) Ab
p-IRAK1 (T209) Ab
p-IRAK1 (T209) Ab
p-IRAK1 (T209) Ab
p-IRAK1 (T209) Ab
p-IRAK1 (T209) Ab
p-IRAK1 (T209) Ab
p-IRAK1 (T209) Ab
p-IRAK1 (T209) Ab
p-IRAK1 (T209) Ab
p-IRAK1 (T209) Ab

产品简介

产品简介

Catalog No.

AY0519

Source

Rabbit pAb

UniProt ID

P51617

Reactivity

Human

Application

WB

Calculated Mol Weight

77 kDa

Observed Mol Weight

77 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

IL1RAK, IRAK, IRAK-1, Interleukin-1 receptor-associated kinase 1, Pelle-like protein kinase, kinase IRAK1, Mplk

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human IRAK1 around the phosphorylation site of T209

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation. Association with MYD88 leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation.

引用文献

引用文献

Cannabidiol-dihydroartemisinin conjugates for ameliorating neuroinflammation with reduced cytotoxicity

期刊名称：

BIOORGANIC & MEDICINAL CHEMISTRY

PMID：

33852975

影响因子：

3.641

应用范围：

WB

检测物种：

Mouse

发表时间：

2021-04-02
Nicotine and its metabolite cotinine target MD2 and inhibit TLR4 signaling

期刊名称：

The Innovation

PMID：

34557761

影响因子：

0

应用范围：

WB

检测物种：

Mouse

发表时间：

2021-04-30

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AY0519

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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