MASP1 heavy chain Ab
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MASP1 heavy chain Ab
Western blot analysis of extracts from A549 cells, treated with etoposide (25uM, 24hours), using MASP1 (heavy chain, Cleaved-Arg448) antibody.
MASP1 heavy chain Ab
MASP1 heavy chain Ab
MASP1 heavy chain Ab
MASP1 heavy chain Ab
MASP1 heavy chain Ab
MASP1 heavy chain Ab
MASP1 heavy chain Ab
MASP1 heavy chain Ab
MASP1 heavy chain Ab
MASP1 heavy chain Ab
MASP1 heavy chain Ab

产品简介

产品简介

Catalog No.

AY0485

Source

Rabbit pAb

UniProt ID

P48740

Reactivity

Human;Rat

Application

WB

Calculated Mol Weight

79 kDa

Observed Mol Weight

44 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

Complement-activating component of Ra-reactive factor [Precursor], EC 3.4.21.-, Ra-reactive factor serine protease p100, RaRF, Mannan-binding lectin serine protease 1, Mannose-binding protein-associated serine protease, MASP-1, Serine protease 5, Complement-activating component of Ra-reactive factor heavy chain, Complement-activating component of Ra-reactive factor light chain, MASP1, CRARF, CRARF1, PRSS5

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human MASP1 heavy chain

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5. Also plays a role in development.

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AY0485

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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