MSH2 Ab
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MSH2 Ab
Immunohistochemistry analysis of paraffin-embedded human brain tissue using MSH2 antibody.
MSH2 Ab
Immunofluorescence analysis of HUVEC cells, using MSH2 antibody.
MSH2 Ab
MSH2 Ab
MSH2 Ab
MSH2 Ab
MSH2 Ab
MSH2 Ab
MSH2 Ab
MSH2 Ab
MSH2 Ab
MSH2 Ab

产品简介

产品简介

Catalog No.

AY0466

Source

Rabbit pAb

UniProt ID

P43246

Reactivity

Human;Mouse;Rat

Application

IHC;ICC/IF;IHF

Calculated Mol Weight

105 kDa

Observed Mol Weight

105 kDa

Recommended Dilution

IHC 1:50-1:100

ICC/IF 1:50-1:200

IHF 1:50-1:100

Alternative Names

COCA1, DNA mismatch repair protein Msh2, FCC1, HNPCC, HNPCC1, MutS protein homolog 2, mutS (E. coli) homolog 2

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human MSH2

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA.

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AY0466

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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