Cleaved-Caspase 3 p17 Ab
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Cleaved-Caspase 3 p17 Ab
Western blot analysis of extracts from 293 cells, treated with Etoposide (25uM, 60mins), using Caspase 3 (cleaved-Asp175) antibody.
Cleaved-Caspase 3 p17 Ab
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue, using Caspase 3 (cleaved-Asp175) antibody.
Cleaved-Caspase 3 p17 Ab
Cleaved-Caspase 3 p17 Ab
Cleaved-Caspase 3 p17 Ab
Cleaved-Caspase 3 p17 Ab
Cleaved-Caspase 3 p17 Ab
Cleaved-Caspase 3 p17 Ab
Cleaved-Caspase 3 p17 Ab
Cleaved-Caspase 3 p17 Ab
Cleaved-Caspase 3 p17 Ab
Cleaved-Caspase 3 p17 Ab

产品简介

产品简介

Catalog No.

AY0458

Source

Rabbit pAb

UniProt ID

P42574

Reactivity

Human;Mouse;Rat

Application

WB;IHC

Calculated Mol Weight

17,32 kDa

Observed Mol Weight

17, 32 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

Apopain precursor, CASP-3, CPP-32, CPP32, Caspase-3, Cysteine protease CPP32, ICE3, SCA-1, SREBP cleavage activity 1, Yama protein

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Other

Immunogen

A synthesized peptide derived from human Caspase 3

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Thiol protease that acts as a major effector caspase involved in the execution phase of apoptosis.Following cleavage and activation by initiator caspases (CASP8, CASP9 and/or CASP10), mediates execution of apoptosis by catalyzing cleavage of many proteins.

引用文献

引用文献

A Novel Fully Human Agonistic Single Chain Fragment Variable Antibody Targeting Death Receptor 5 with Potent Antitumor Activity In Vitro and In Vivo

期刊名称：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PMID：

28953230

影响因子：

3.226

应用范围：

ICC/IF

检测物种：

Mouse

发表时间：

2017-09-27
Combination of novel DR5 targeting agonistic scFv antibody TR2-3 with cisplatin shows enhanced synergistic antitumor activity in vitro and in vivo

期刊名称：

BIOMEDICINE & PHARMACOTHERAPY

PMID：

29272788

影响因子：

2.759

应用范围：

WB,ICC/IF

检测物种：

Mouse,Human

发表时间：

2017-12-27
Rev-erbα Inhibits Proliferation and Promotes Apoptosis of Preadipocytes through the Agonist GSK4112

期刊名称：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PMID：

31547330

影响因子：

4.183

应用范围：

WB

检测物种：

Mouse

发表时间：

2019-09-12
Grpel2 alleviates myocardial ischemia/reperfusion injury by inhibiting MCU-mediated mitochondrial calcium overload

期刊名称：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PMID：

35447394

影响因子：

3.322

应用范围：

WB

检测物种：

Mouse

发表时间：

2022-04-08
Resveratrol improves estrus disorder induced by bisphenol A through attenuating oxidative stress, autophagy, and apoptosis

期刊名称：

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

PMID：

35670589

影响因子：

3.568

应用范围：

WB

检测物种：

Mouse

发表时间：

2022-06-07
A derivant of ginsenoside CK and its inhibitory effect on hepatocellular carcinoma

期刊名称：

LIFE SCIENCES

PMID：

35690105

影响因子：

6.78

应用范围：

IHC,WB

检测物种：

Mouse,Human

发表时间：

2022-06-08

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AY0458

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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