p-FLT3 (Y842) Ab

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p-FLT3 (Y842) Ab
Western blot analysis of extracts from HepG2 cells, treated with EGF (200ng/ml, 30mins), using FLT3 (Phospho-Tyr842)) antibody.
p-FLT3 (Y842) Ab
p-FLT3 (Y842) Ab
p-FLT3 (Y842) Ab
p-FLT3 (Y842) Ab
p-FLT3 (Y842) Ab
p-FLT3 (Y842) Ab
p-FLT3 (Y842) Ab
p-FLT3 (Y842) Ab
p-FLT3 (Y842) Ab
p-FLT3 (Y842) Ab
p-FLT3 (Y842) Ab

产品简介

产品简介

Catalog No.

AY0444

Source

Rabbit pAb

UniProt ID

Reactivity

Human;Mouse

Application

WB

Calculated Mol Weight

113 kDa

Observed Mol Weight

160 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

CD135; EC 2.7.10.1; fetal liver kinase 2; FL cytokine receptor; FLK-2; FLT-3; FLT3; fms-related tyrosine kinase 3; kinase Flt3; stem cell tyrosine kinase 1; STK-1; STK1

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human FLT3 around the phosphorylation site of Y842

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Tyrosine-protein kinase that acts as a cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES, FER, PTPN6/SHP, PTPN11/SHP-2, PLCG1, and STAT5A and/or STAT5B.

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AY0444

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

次日发货

订购信息:

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